Personal Data

Name: Ana Rita Lourenco INACIO
Business Address: Institut de Neurobiologie de la Méditerranée INMED UMR901,
163 avenue de Luminy BP13 - 13273 Marseille cedex 09 - France
Phone: +33 4 91 82 81 41
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Date of Birth: 25.04.1983


Education and Academic Degrees

2011, PhD in Medical Science, Faculty of Medicine, Lund University, Lund, Sweden
2001-2006, Graduated with Honors, Biochemistry, Department of Biochemistry, Faculty of Sciences and Technology, University of Coimbra, Portugal


Positions held

2012 - present, Postdoctoral fellow, Institut de Neurobiologie de la Méditerranée (INMED); advisor: Dr. R. Khazipov
2012 - Researcher, Laboratory for Experimental Brain Research; advisor: Dr. T. Wieloch
2007-2011, Graduate student Laboratory for Experimental Brain Research, Department of Neurosurgery Faculty of Medicine, Lund University, Sweden; advisors: Dr. T. Wieloch and Dr. T. Deierborg
2005-2006, Undergraduate student, Neuronal Survival Unit, Department of Experimental Medical Sciences Faculty of Medicine, Lund University, Sweden; advisors: Dr. P. Brundin and Dr. T. Deierborg


Areas of Specializations

  • Neuroscience, development of the sensorimotor system
  • Medical Science, role of classic pro- and anti-inflammatory mediators in ischemic stroke
  • Medical Science, adult neurogenesis in animal models of stroke and excitotoxicity



  • 2013-2015, Marie Curie Intra-European Fellowship, FP7-PEOPLE-2012-IEF
  • 2011, Scholarship from the Faculty of Medicine, Lund University, Sweden
  • 2006-2010, Competitive Ph.D. scholarship from the Fundação para a Ciência e a Tecnologia, Ministério da Educação e Ciência, Portugal (
  • 2005-2006, Scholarship from the Socrates/Erasmus exchange program, Portugal


Research grants

2011, Grant from the Royal Physiographic Society in Lund, Sweden (for the project: macrophage migration inhibitory factor modulates the inflammatory/immune response after experimental stroke)


Travel awards

2012, Award for best poster, Neuroscience Day, Lund University, Lund, Sweden (The Society for Neuroscience Annual Meeting, New Orleans, L.A., USA)
2010, Travel stipend from the Royal Physiographic Society in Lund, Sweden (The Society for Neuroscience Annual Meeting, Washington, D.C., USA)



Isoflurane suppresses early cortical activity

Guzel Sitdikova, Andrei Zakharov, Sona Janackova, Elena Gerasimova, Julia Lebedeva, Ana R. Inacio, Dilyara Zaynutdinova, Marat Minlebaev, Gregory L. Holmes, Roustem Khazipov; Annals of Clinical and Translational Neurology 2014; 1(1): 15–26 PDF

Gamma Oscillations in the Somatosensory Cortex of Newborn Rats

E. V. Gerasimova, A. V. Zakharov, Yu. A. Lebedeva, A. R. Inacio, M. G. Minlebaev, G. F. Sitdikova, and R. N. Khazipov; Bulletin of Experimental Biology and Medicine, Vol. 156, No. 3, January, 2014 PDF


Curcio M, Inácio AR, Duarte EP, Canzoniero LMT, Salazar I, Duarte CB (2014) Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons. Cell Death and Disease (accepted for publication)

Mele M, Ribeiro L, Inácio AR, Wieloch T, Duarte CB (2014) GABA(A) receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia. Neurobiol Dis 65:220-32.

Ruscher K, Inácio AR, Valind K, Rowshan Ravan A, Kuric E, Wieloch T (2012) Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke. PloS ONE 7(9):e45118.

Gomes JR, Costa JT, Melo CV, Felizzi F, Monteiro P, Pinto MJ, Inácio AR, Wieloch T, Almeida RD, Grãos M, Duarte CB (2012) Excitotoxicity downregulates TrkB.FL signaling and upregulates the neuroprotective truncated TrkB receptors in cultured hippocampal and striatal neurons. J Neurosci 32(13):4610-22.

Lobo AC, Gomes JR, Catarino T, Mele M, Fernandez P, Inácio AR, Bahr BA, Santos AE, Wieloch T, Carvalho AL, Duarte CB (2011) Cleavage of the vesicular glutamate transporters under excitotoxic conditions. Neurobiol Dis 44(3):292-303.

Inácio AR, Bucala R, Deierborg T (2011) Lack of macrophage migration inhibitory factor in mice does not affect hallmarks of the inflammatory/immune response during the first week after stroke. J Neuroinflamm 8(1):75.

Gomes JR, Lobo AE, Melo CV, Inácio AR, Takano J, Iwata N, Saido TC, de Almeida LP, Wieloch T, Duarte CB (2011) Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites. J Neurosci 31(12):4622-35.

Inácio AR, Ruscher K, Leng L, Bucala R, Deierborg T (2011) Macrophage migration inhibitory factor promotes cell death and aggravates neurological deficits following experimental stroke. J Cereb Blood Flow Metab 31(4):1093-106.

Inácio AR, Ruscher K, Wieloch T (2011) Enriched environment downregulates macrophage migration inhibitory factor and increases parvalbumin in the brain following experimental stroke. Neurobiol Dis 41(2):270-8.

Deierborg T, Roybon L, Inácio AR, Pesic J, Brundin P (2010) Brain injury activates microglia that induce neural stem cell proliferation ex vivo and promote differentiation of neurosphere-derived cells into neurons and oligodendrocytes. Neuroscience 171(4):1386-96.

Ishizaki T, Erikson A, Kuric E, Shamloo M, Hara-Nishimura I, Inácio AR, Wieloch T, Ruscher K (2010) The asparaginyl endopeptidase legumain after experimental stroke. J Cereb Blood Flow Metab 30(10):1756-66.

Ruscher K, Erikson A, Kuric E, Inácio AR, Wieloch T (2010) Effects of chronic Clozapine administration on apolipoprotein D levels and on functional recovery following experimental stroke. Brain Res 1321:152-63.